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GLP-1RA/tesaglitazar does not differ from the pharmacokinetically matched GLP-1RA in GLP-1R signalling, but shows GLP-1R-dependent PPAR-retinoic acid receptor heterodimerization and enhanced improvements of body weight, food intake and glucose metabolism relative to the GLP-1RA or tesaglitazar alone in obese male mice
It can worsen anxiety and should be avoided by people with a history of psychosis
and is "thoroughly vetted by third party scientific and medical experts for claims and safety," the company added
It enhances energy production and preserves lean muscle during training
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